Is obesity associated with increased plasma lipid peroxidation and oxidative stress in women? ARYA Atherosclerosis, 2(4), 189-192. They befriended the self-styled ruler of Terminus, a mad planetar named. Clinical Chemistry, 20(4), 470-475.Īmirkhizi, F., Siassi, F., Minaie, S., Djalali, M., Rahimi, A., & Chamari, M. They ultimately located Ras Nsi within a shrine of Ubtao called the House of the. Enzymatic determination of total serum cholesterol. Toxicology and Industrial Health, 31(2), 179-187.Īllain, C. Effects of trona on the redox status of cellular system of male rats. High density lipoprotein cholesterol, total cholesterol screening, and myocardial infarction. American Journal of Research in Medical Sciences, 2(1), 73-79.Ībbott, R. Antioxidant enzymes and minerals status of diabetic subjects supplemented with antioxidant rich supplement (alphabetic). A high concentration of natron can be used to induce an animal model of PPCM, which would be of practical application in studying the molecular basis and possible discovery of therapeutics for the disease.Īntioxidant status dyslipidemia natron oxidative stress rat.Ībbas, A., Abdullahi, Z., Saidu, Y., Sabir, A., Ladan, M., Ikeonu, F., & Dalhat, M.
The results suggest that OS due to natron may contribute to the pathogenesis of PPCM. Natron has health benefits however, its consumption at high doses should be discouraged as it can lead to oxidative stress (OS) and dyslipidemia. PRACTICAL APPLICATION: This research reports the implication of a high intake of natron to health and to establish the relationship between natron intake and peripartum cardiomyopathy (PPCM) using an animal model. This study demonstrated that the administration of natron at high doses induced dyslipidemia and oxidative stress in postpartum rats. Natron at higher doses caused a significant increase (P ˂ 0.05) in the level of the lipid profile parameters except for high-density lipoprotein-cholesterol that decrease significantly (P ˂ 0.05). There was a significant increase (P < 0.05) in the malondialdehyde level in rats administered with 200 and 300 mg/kg of natron when compared with control. Serum levels of antioxidant minerals were also significantly decreased (P ˂ 0.05) at higher doses of natron in comparison to control. The activities of superoxide dismutase and glutathione peroxidase decreased in a dose-dependent manner however, the difference was not statistically significant when compared with control. The results revealed that natron caused a significant decrease (P ˂ 0.05) in the activity of catalase in rats administered with 300 mg/kg of natron compared to control.
After treatment, the rats were assessed for antioxidant status, malondialdehyde level, and lipid profile. This work evaluates the effect of natron on the antioxidant status and lipid profile of postpartum rats administered graded doses of natron for four consecutive weeks. Natron consumption has been implicated in the pathogenesis of peripartum cardiomyopathy. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators.
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